mAb production kinetics in CHO batch culture: exploring extracellular and intracellular dynamics

Publication in "Frontiers in Bioengineering and Biotechnology"

Alejandro Avilan Garzon, David Pfister (Ypso-Facto), Bruno Ebel, Samuel Schneider, Eric Olmos (université de Lorraine), Cédric Paris (LIBio)

• by Ypso-Facto
• August 13, 2025

We are pleased to announce that Alejandro Avilan Garzon, PhD, doctoral researcher conducting his PhD work at Ypso-Facto, has recently published part of his research in Frontiers in Bioengineering and Biotechnology, in collaboration with our colleague David Pfister.

The study investigates key aspects of monoclonal antibody (mAb) production in CHO batch cultures, combining extracellular and intracellular data to gain a deeper understanding of process dynamics.

This work contributes to our ambition to apply Ypso-Facto’s proven DSP methodology to the optimization of upstream processes.

Read the full article here

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